The Heterocycles of the Context of COVID-19 (Part 2): Contribution of Junior Scientific Initiation for the Process of (Re)signifying Chemical Concepts

The present writing composes the second part of clippings of the practice of a junior scientific initiation project and intends to highlight the contribution of the study of molecules correlated to the COVID-19 pandemic theme for the delimitation of fundamental concepts in the field of organic chemistry. The methodology adopted (supported by a virtual didactic workshop, scientific texts and teaching materials) involved high school students in a collective effort in the face of the debate on controversial aspects of the pandemic. As a result, we point out the possibility of addressing important structural chemical concepts and formulas that underlie the area of organic chemistry and, more specifically, heterocyclic chemistry. In this writing, we share a brief account of our experience regarding the use of this thematic in an investigative journey with the school students.

The Heterocycles in the Context of COVID-19 (Part 1): a Review with Highlights of the Pandemic

This article is a mirror of the initial clippings of a project junior scientific initiation project and aims to make available a scientific text, in Portuguese language, built in the light of the main highlights that brought the chloroquine and hydroxychloroquine into the spotlight of the current pandemic context. In view of this context, the objective of this article, of an eminently theoretical nature, is to contribute to the delimitation of fundamental concepts in the field of organic chemistry. The methodology adopted for this descriptive and exploratory research, with a qualitative approach, consisted of systematically reviewing the literature, using indexed databases, to contextualize factual points about the historical origin (natural and synthetic) and the pharmacological properties of heterocycles correlated to the theme of COVID-19 pandemic. We approach concepts and structural chemical formulas that support the area of organic chemistry and, more specifically, heterocyclic chemistry. And, through this compilation, we present a way of quick access to the recent information anchored in journals of national and international impact.